Vitamin B3 (Niacinamide) is an important vitamin for maintaining a healthy cardiovascular system and metabolism, especially balancing blood cholesterol levels. Helps with brain function, healthy skin formation and maintenance, and even preventing or treating diabetes.

Symptoms Linked to B3 (Niacinamide) Deficiency:

  • Brain impairment and psychosis – impaired consciousness, cognitive decline (dementia), disorientation, confusion, depression, mania, or paranoia
  • Gastrointestinal (digestive) disturbances – symptoms include burning in the pharynx and esophagus, stomach and abdominal discomfort, constipation, nausea, vomiting, and diarrhea
  • Skin symptoms include several types of lesions
  • Pellagra – characterized by skin inflammation, hallucinations, digestive distress. Usually occurs in malnourished people or those with alcoholism and can include rash, stomatitis, diarrhea, and mental problems.
  • Mucous membrane swelling – symptoms which affect the mouth, vagina and urethra tongue can cause pain in the mouth, increased salivation, and edema of the tongue, and ulcers.

Health Problems Associated to B3 (Niacinamide) Deficiency: 

  • Diabetes – B3 preserves B-cell function in type 1 diabetics. B3 is part of (GTF) glucose tolerance factor which facilitates insulin binding.
  • Anxiety – One of the symptoms of severe B3 deficiency (pellagra) is anxiety. Pharmacological doses of B3 may enhance the calming effects of GABA in the brain. Converts tryptophan to serotonin.
  • Dyslipidemia – Niacin (B3) effectively lowers the highly atherogenic Lp(a) by decreasing its rate of synthesis in the liver.
  • Fatigue – B Vitamins are necessary for converting food into energy. Cofactors in the mitochondrial respiratory chain include B1, B2, B3, B5, B6, B12 and Folate (B9).
  • Headaches – B3 dilates blood vessels. Increases serotonin.
  • Insomnia – Niacin (B3) increases REM sleep. Improves both quality and quantity of sleep by converting tryptophan to serotonin.
  • Methylation – B3 maintains proper methylation of genes that suppress tumor formation and growth.
  • Sports Nutrition – B vitamins are cofactors for efficient energy metabolism from food. Synthesizing red blood cells require Folate (B9) and B12. Deficiencies in various B vitamins may slow healing in sports injuries.
  • Telomeres – B3 extends lifespan of human cells in vitro. Slows telomere attrition rate by reducing reactive oxygen species in mitochondria.
  • Weight Management – Treatment with B3 increases adiponectin, a weight-loss hormone secreted by fat cells. Niacin-bound chromium supplements helped educed body weight in clinical trials.

How to Acquire B3 (Niacinamide):

  • Beef Liver
  • Chicken Breast
  • Tuna
  • Sunflower Seeds
  • Grass-fed Beef or Lamb
  • Salmon
  • Sardines
  • Turkey

Clinical Updates on B3 (Niacinamide)